RT Journal Article
SR Electronic
T1 Effect of artificial pancreas treatment on peripheral nerve function in diabetes
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 1375
OP 1375
DO 10.1212/WNL.31.11.1375
VO 31
IS 11
A1 Service, F. J.
A1 Daube, J. R.
A1 O'Brien, P. C.
A1 Dyck, P. J.
YR 1981
UL http://n.neurology.org/content/31/11/1375.abstract
AB To determine whether the complete correction of hyperglycemia of diabetes can rapidly improve abnormal peripheral nerve function, eight hyperglycemic insulin-requiring diabetics underwent 3 days of glucose control with an artificial endocrine pancreas, the BIOSTATORB Glucose Controller. Comparison of neurologic assessment before and after BIOSTATOR treatment showed improvement only in ulnar sensory conduction velocity (+ 3.2 21.4 meters per second, p < 0.032) and no significant changes in 24 other nerve conduction measurements, computer-assisted sensory examination, and scored neurologic assessment. Any significant beneficial effect on nerve function resulting from correction of hyperglycemia probably requires more than 3 days to be manifested.