PT - JOURNAL ARTICLE AU - Filley, Christopher M. AU - Graff-Radford, Neill R. AU - Lacy, Joseph R. AU - Heitner, Mark A. AU - Earnest, Michael P. TI - Neurologic manifestations of podophyllin toxicity AID - 10.1212/WNL.32.3.308 DP - 1982 Mar 01 TA - Neurology PG - 308--308 VI - 32 IP - 3 4099 - http://n.neurology.org/content/32/3/308.short 4100 - http://n.neurology.org/content/32/3/308.full SO - Neurology1982 Mar 01; 32 AB - A young woman presented with podophyllin intoxication following topical application of podophyllin resin to genital condylomata acuminata. The disorder was marked by hallucinatory psychosis, bone marrow depression, and mild hepatic dysfunction. The psychosis and systemic disturbances resolved within 3 weeks, but were followed by autonomic and sensorimotor peripheral neuropathy. This case illustrates the transient central neurotoxicity and persistent peripheral neurotoxicity of podophyllin.