RT Journal Article
SR Electronic
T1 Neuropathologic evaluation of 40 confirmed cases of <em>Legionella</em> pneumonia
JF Neurology
JO Neurology
FD Lippincott Williams &amp; Wilkins
SP 1340
OP 1340
DO 10.1212/WNL.33.10.1340
VO 33
IS 10
A1 Pendlebury, William W.
A1 Perl, Daniel P.
A1 Winn, Washington C.
A1 McQuillen, James B.
YR 1983
UL http://n.neurology.org/content/33/10/1340.abstract
AB Autopsy examination of the brain was performed in 40 cases of Legionella pneumonia. Thirty-nine of 40 patients had underlying chronic or acute medical problems. Sixteen patients (40%) had neurologic signs or symptoms that were not explained by preexisting disease. CSF was normal in six of seven patients examined; CSF protein content was 66 mg/100 ml in one patient. Neuropathologic examination in all 40 patients demonstrated no lesions attributable to disseminated Legionella pneumophila. Mechanisms other than direct cerebral invasion by the causative organism must be sought to explain the neurologic manifestations of Legionella pneumonia.