PT  - JOURNAL ARTICLE
AU  - Shapira, Yehuda A.
AU  - Patz, David
AU  - Menczel, Jacob
AU  - Schwartz, Lydia
AU  - Meyer, Shirley
AU  - Frutkoff, Irving W.
AU  - Kidroni, Gideon
TI  - Low serum 24,25 dihydroxyvitamin D in Duchenne muscular dystrophy
AID  - 10.1212/WNL.34.9.1192
DP  - 1984 Sep 01
TA  - Neurology
PG  - 1192--1192
VI  - 34
IP  - 9
4099  - http://n.neurology.org/content/34/9/1192.short
4100  - http://n.neurology.org/content/34/9/1192.full
SO  - Neurology1984 Sep 01; 34
AB  - Levels of serum 24,25(OH)2D3 (0.69 ± 0.17 ng/ml) were lower in DMD patients than in age-matched controls (2.13 ± 0.15 ng/ml). Circulating levels of 1,25(OH)2D3 and 25(OH)D3 were within the accepted normal range. Bearing in mind the proposed pathophysiologic role of calcium in DMD and the influence of vitamin D metabolites on muscle ATP and protein synthesis, as well as on sarcoplasmic reticulum calcium transport and muscle mitochondrial calcium content, the above findings of low or deficient 24,25(OH)2D3 levels in DMD could be meaningful from the etiologic and therapeutic points of view.