RT Journal Article
SR Electronic
T1 Inflammatory neuroprithy in homosexual men with lymphadenopathy
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 1479
OP 1479
DO 10.1212/WNL.35.10.1479
VO 35
IS 10
A1 Lipkin, W. Ian
A1 Parry, Gareth
A1 Kiprov, Dobri
A1 Abrams, Donald
YR 1985
UL http://n.neurology.org/content/35/10/1479.abstract
AB Twelve homosexual men had peripheral neuropathy with fever, night sweats, and lymphadenopathy. Sensory symptoms predominated, but there was also weakness and cranial nerve dysfunction. Manifestations were multifocal in nine and distal and symmetric in three. CSF was abnormal in all eight patients examined. Sural nerve in five patients showed axonal degeneration, accompanied in two by segmental demyelination. Four patients had epineurial and endoneurial perivascular chronic inflammatory cells without evidence of vasculitis. Neuropathy remitted spontaneously in six patients. Four patients received steroids without clinical response, although one later responded to plasmapheresis-lymphocytapheresis. Four patients later progressed to AIDS.