PT - JOURNAL ARTICLE AU - Hauser, Stephen L. AU - Fosburg, Martin AU - Kevy, Sherwin V. AU - Weiner, Howard L. TI - Lymphocytapheresis in chronic progressive multiple sclerosis AID - 10.1212/WNL.34.7.922 DP - 1984 Jul 01 TA - Neurology PG - 922--922 VI - 34 IP - 7 4099 - http://n.neurology.org/content/34/7/922.short 4100 - http://n.neurology.org/content/34/7/922.full SO - Neurology1984 Jul 01; 34 AB - We studied the effects of lymphocytapheresis in five patients with chronic progressive MS. Ten lymphocytapheresis treatments were given in 2 weeks, followed by 1 treatment every 2 weeks for 2 to 6 months. Four of five patients had a fall in the circulating lymphocyte count during the initial treatment, and in three patients a modest lymphopenia was sustained with maintenance therapy. In patients with abnormal T4:T8 ratios, no improvement in the T4:TS ratio occurred. There was no apparent clinical effect in this pilot study.