RT Journal Article
SR Electronic
T1 Lymphocytapheresis in chronic progressive multiple sclerosis
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 922
OP 922
DO 10.1212/WNL.34.7.922
VO 34
IS 7
A1 Hauser, Stephen L.
A1 Fosburg, Martin
A1 Kevy, Sherwin V.
A1 Weiner, Howard L.
YR 1984
UL http://n.neurology.org/content/34/7/922.abstract
AB We studied the effects of lymphocytapheresis in five patients with chronic progressive MS. Ten lymphocytapheresis treatments were given in 2 weeks, followed by 1 treatment every 2 weeks for 2 to 6 months. Four of five patients had a fall in the circulating lymphocyte count during the initial treatment, and in three patients a modest lymphopenia was sustained with maintenance therapy. In patients with abnormal T4:T8 ratios, no improvement in the T4:TS ratio occurred. There was no apparent clinical effect in this pilot study.