RT Journal Article
SR Electronic
T1 Effects of corpus callosum section on secondary bilaterally synchronous interictal EEG discharges
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 1689
OP 1689
DO 10.1212/WNL.35.12.1689
VO 35
IS 12
A1 Susan S. Spencer
A1 Dennis D. Spencer
A1 Peter D. Williamson
A1 Richard H. Mattson
YR 1985
UL http://n.neurology.org/content/35/12/1689.abstract
AB We studied the effect of corpus callosum section on secondary bilaterally synchronous interictal EEG discharges in 13 patients with partial and secondarily generalized seizures before and after partial or complete section of the corpus callosum. Bilaterally synchronous discharges were completely eliminated in one patient. In 12 patients, there was a distinct reduction in frequency. Our clinical experience agrees with experimental data to suggest that epileptic discharges follow pathways, both across the corpus callosum and/or down to diencephalic/mesencephalic structures, before there is bilateral spread.