RT Journal Article
SR Electronic
T1 Survival in Alzheimer's disease and vascular dementias
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 834
OP 834
DO 10.1212/WNL.35.6.834
VO 35
IS 6
A1 Laurie L. Barclay
A1 Alexander Zemcov
A1 John P. Blass
A1 Joseph Sansone
YR 1985
UL http://n.neurology.org/content/35/6/834.abstract
AB Over 5 years, we followed 199 patients with dementia of the Alzheimer type (DAT), 69 with multi-infarct dementia (MID), and 43 with mixed dementia (MIX). All three diagnostic categories had comparable progression of behavioral and cognitive impairment and need for home care or institutionalization at follow-up. However, 50% survival from diagnosis was 2.6 years for MID and 2.5 years for MIX, compared with 3.4 years for DAT. The 50% survivals from onset were longer than previous reports would suggest (8.1 years for DAT, 6.7 for MID, and 6.2 for MIX). Vascular dementias have higher mortality than DAT, even when associated with comparable cognitive and behavioral impairment.