PT  - JOURNAL ARTICLE
AU  - Robert E. Burke
AU  - Stanley Fahn
AU  - C. David Marsden
TI  - Torsion dystonia
AID  - 10.1212/WNL.36.2.160
DP  - 1986 Feb 01
TA  - Neurology
PG  - 160--160
VI  - 36
IP  - 2
4099  - http://n.neurology.org/content/36/2/160.short
4100  - http://n.neurology.org/content/36/2/160.full
SO  - Neurology1986 Feb 01; 36
AB  - We studied trihexyphenidyl in the treatment of torsion dystonia in a prospective, double-blind crossover protocol. Thirty-one patients completed the protocol. Twenty-two (71%) had a clinically significant response. After a mean follow-up of 2.4 years, 68% of patients continued to take trihexyphenidyl, and 42% continued to show a considerable or dramatic benefit. The 30-mg dose used was generally well tolerated. High-dosage trihexyphenidyl therapy is effective in the management of torsion dystonia.