RT Journal Article
SR Electronic
T1 Subacute sclerosing panencephalitis: remission after treatment with intraventricular interferon
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 562
OP 566
DO 10.1212/WNL.36.4.562
VO 36
IS 4
YR 1986
UL http://n.neurology.org/content/36/4/562.abstract
AB Three children with stage II-III subacute sclerosing panencephalitis (SSPE) were treated with intraventricular human leukocyte interferon for 6 months. All three improved to varying degrees and for different lengths of time. Clinical remissions were associated with decreased titers of antibody to measles virus in CSF and with reduced rates of intrathecal IgG synthesis. There were no serious complications or side effects. Intraventricular interferon deserves further study as a potential therapeutic agent in SSPE.