PT  - JOURNAL ARTICLE
AU  - Creasey, Helen
AU  - Schwartz, Michael
AU  - Frederickson, Harold
AU  - Haxby, James V.
AU  - Rapoport, Stanley I.
TI  - Quantitative computed tomography in dementia of the Alzheimer type
AID  - 10.1212/WNL.36.12.1563
DP  - 1986 Dec 01
TA  - Neurology
PG  - 1563--1563
VI  - 36
IP  - 12
4099  - http://n.neurology.org/content/36/12/1563.short
4100  - http://n.neurology.org/content/36/12/1563.full
SO  - Neurology1986 Dec 01; 36
AB  - Men and women with dementia of the Alzheimer type (DAT) had more brain atrophy and ventricular dilatation, measured by quantitative CT, than did respective age- and sex-matched healthy controls (p < 0.05). The male DAT patients with mild dementia had a larger mean third ventricle volume, whereas male patients with severe dementia had larger lateral and third ventricle volumes, more CSF, and less gray matter than did controls. Statistically significant and appropriate correlations between several dementia scales and CT measures in the DAT patients indicated that brain atrophy and ventricular dilatation were related to the severity of dementia.