PT  - JOURNAL ARTICLE
AU  - van Doorn, Pieter A.
AU  - Brand, Anneke
AU  - Vermeulen, Marinus
TI  - Clinical significance of antibodies against peripheral nerve tissue in inflammatory polyneuropathy
AID  - 10.1212/WNL.37.11.1798
DP  - 1987 Nov 01
TA  - Neurology
PG  - 1798--1798
VI  - 37
IP  - 11
4099  - http://n.neurology.org/content/37/11/1798.short
4100  - http://n.neurology.org/content/37/11/1798.full
SO  - Neurology1987 Nov 01; 37
AB  - With the use of a mixed hemagglutination test (MHT), circulating antibodies against human peripheral nerve tissue (PNT) were found in 22 of 38 patients with Guillain-Barré syndrome (GBS) or chronic relapsing demyelinating inflammatory polyneuropathy (CR-DIP). The antibodies were found in only 1 of 34 patients with polyneuropathy of other origin, and in 3 of 32 patients without polyneuropathy. The presence of antibodies was related to response to intravenous gamma globulin treatment in CR-DIP patients. Antibodies against PNT may be pathogenic.