PT - JOURNAL ARTICLE AU - Masur, H. AU - Elger, C. E. AU - Ludolph, A. C. AU - Galanski, M. TI - Cerebellar atrophy following acute 0intoxication with phenytoin AID - 10.1212/WNL.39.3.432 DP - 1989 Mar 01 TA - Neurology PG - 432--432 VI - 39 IP - 3 4099 - http://n.neurology.org/content/39/3/432.short 4100 - http://n.neurology.org/content/39/3/432.full SO - Neurology1989 Mar 01; 39 AB - A patient developed marked cerebellar atrophy after a single suicidal intoxication with 7 grams phenytoin. The clinical signs of cerebellar dysfunction subsided very slowly and incompletely within 18 months. We documented the cerebellar atrophy by CTs 4 weeks and 1 year after the intoxication, and we suggest that a single severe acute intoxication with phenytoin may directly cause cerebellar degeneration.