RT Journal Article SR Electronic T1 Magnetic resonance findings in REM sleep behavior disorder JF Neurology JO Neurology FD Lippincott Williams & Wilkins SP 1519 OP 1519 DO 10.1212/WNL.39.11.1519 VO 39 IS 11 A1 Antonio Culebras A1 James T. Moore YR 1989 UL http://n.neurology.org/content/39/11/1519.abstract AB Rapid eye movement (REM) sleep behavior disorder is characterized by bizarre acts during nocturnal sleep that may lead to physical injuries. Dream content suggests that motor overactivity is an attempted dream enactment and polygraphic studies reveal REM stage without atonia, an alteration of REM sleep generation that facilitates excessive motor activity. In 6 patients with REM sleep behavior disorder, MRI of the brain showed multifocal signal intensity lesions suggestive of lacunar infarcts in periventricular regions (5 patients) and in dorsal pontomesencephalic areas (3 patients). REM sleep behavior disorder may be the result of injury to the midrostral tegmentum nuclei, the tegmentoreticular tracts, or both. This condition is easily controlled with clonazepam.