RT Journal Article
SR Electronic
T1 Visuospatial impairment in Parkinson's disease
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 365
OP 365
DO 10.1212/WNL.41.3.365
VO 41
IS 3
A1 Levin, B. E.
A1 Llabre, M. M.
A1 Reisman, S.
A1 Weiner, W. J.
A1 Sanchez-Ramos, J.
A1 Singer, C.
A1 Brown, M. C.
YR 1991
UL http://n.neurology.org/content/41/3/365.abstract
AB We explored the nature of the visuospatial deficit in Parkinson's disease (PD) and its progression as a function of disease duration. We compared the performance of 183 patients with idiopathic PD and 90 control subjects matched for age and education on six visuospatial measures. We divided patients into three groups according to the disease duration: early (1 to 4 years), middle (5 to 10 years), and advanced (> 10 years). Performance deteriorated in five of the six visuospatial measures, as a function of disease duration. However, the pattern of visuospatial decline depended on whether dementia was present. The results were not influenced by age or anticholinergic medication. These findings support the presence of visuospatial deficits in PD patients, with a changing pattern of impairment related to dementia and progression of the disease.