PT  - JOURNAL ARTICLE
AU  - Camerlingo, M.
AU  - Finazzi, G.
AU  - Casto, L.
AU  - Laffranchi, C.
AU  - Barbui, T.
AU  - Mamoli, A.
TI  - Inherited protein C deficiency and nonhemorrhagic arterial stroke in young adults
AID  - 10.1212/WNL.41.9.1371
DP  - 1991 Sep 01
TA  - Neurology
PG  - 1371--1371
VI  - 41
IP  - 9
4099  - http://n.neurology.org/content/41/9/1371.short
4100  - http://n.neurology.org/content/41/9/1371.full
SO  - Neurology1991 Sep 01; 41
AB  - Out of a consecutive series of 50 young people less than 45 years old with nonhemorrhagic arterial stroke, three patients had inherited protein C deficiency. CT revealed hypodense areas consistent with the clinical picture, and angiography showed occlusion of some intracranial arterial vessels. Other possible associated causes of stroke were ruled out. One patient had a transient ischemic attack and a peripheral venous thrombosis prior to the actual stroke, whereas the others were completely asymptomatic, as were relatives with the same deficiency. We suggest determining protein C in ischemic stroke of all young adults, especially when major risk factors are excluded.