PT - JOURNAL ARTICLE AU - Malm, Jan AU - Kristensen, Bo AU - Markgren, Peter AU - Ekstedt, Jan TI - CSF hydrodynamics in idiopathic intracranial hypertension AID - 10.1212/WNL.42.4.851 DP - 1992 Apr 01 TA - Neurology PG - 851--851 VI - 42 IP - 4 4099 - http://n.neurology.org/content/42/4/851.short 4100 - http://n.neurology.org/content/42/4/851.full SO - Neurology1992 Apr 01; 42 AB - To examine CSF hydrodynamics, we studied 16 patients with idiopathic intracranial hypertension and 45 control subjects with a constant-pressure infusion method. Fifteen patients had 155 examinations up to 15 years after the onset of disease. In most patients, the disturbances of CSF hydrodynamics persisted for many years. We identified at least two mechanisms for the development of the increased CSF pressure: a rise of sagittal sinus pressure, probably explained by extracellular edema causing partial compression of the major venous sinus (type 1), or a low conductance with a compensatory increase in CSF pressure in order to sustain the bulk flow (type 2).