RT Journal Article
SR Electronic
T1 CSF hydrodynamics in idiopathic intracranial hypertension
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 851
OP 851
DO 10.1212/WNL.42.4.851
VO 42
IS 4
A1 Malm, Jan
A1 Kristensen, Bo
A1 Markgren, Peter
A1 Ekstedt, Jan
YR 1992
UL http://n.neurology.org/content/42/4/851.abstract
AB To examine CSF hydrodynamics, we studied 16 patients with idiopathic intracranial hypertension and 45 control subjects with a constant-pressure infusion method. Fifteen patients had 155 examinations up to 15 years after the onset of disease. In most patients, the disturbances of CSF hydrodynamics persisted for many years. We identified at least two mechanisms for the development of the increased CSF pressure: a rise of sagittal sinus pressure, probably explained by extracellular edema causing partial compression of the major venous sinus (type 1), or a low conductance with a compensatory increase in CSF pressure in order to sustain the bulk flow (type 2).