RT Journal Article
SR Electronic
T1 Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 1743
OP 1743
DO 10.1212/WNL.42.9.1743
VO 42
IS 9
A1 Watson, C.
A1 Andermann, F.
A1 Gloor, P.
A1 Jones-Gotman, M.
A1 Peters, T.
A1 Evans, A.
A1 Olivier, A.
A1 Melanson, D.
A1 Leroux, G.
YR 1992
UL http://n.neurology.org/content/42/9/1743.abstract
AB Both the amygdala and the hippocampus are involved in the pathogenesis of a number of neurologic conditions, including temporal lobe epilepsy, postanoxic amnesia, and Alzheimer's disease. To enhance the investigation and management of patients with these disorders, we developed a protocol to measure the volumes of the amygdala and as much of the hippocampus as possible (approximately 90 to 95%) using high-resolution MRI. We present the anatomic basis of these two protocols and our results in normal control subjects. These volumetric studies of the amygdala may clarify the role of this structure in the pathogenesis of temporal lobe epilepsy.