PT  - JOURNAL ARTICLE
AU  - M. Mirabella
AU  - S. Servidei
AU  - G. Manfredi
AU  - E. Ricci
AU  - A. Frustaci
AU  - E. Bertini
AU  - M. Rana
AU  - P. Tonali
TI  - Cardiomyopathy may be the only clinical manifestation in female carriers of Duchenne muscular dystrophy
AID  - 10.1212/WNL.43.11.2342
DP  - 1993 Nov 01
TA  - Neurology
PG  - 2342--2342
VI  - 43
IP  - 11
4099  - http://n.neurology.org/content/43/11/2342.short
4100  - http://n.neurology.org/content/43/11/2342.full
SO  - Neurology1993 Nov 01; 43
AB  - Cardiomyopathy was reported in a few Duchenne muscular dystrophy (DMD) carriers with clinical evidence of myopathy. We report two carriers with dilated cardiomyopathy, increased serum CK, and no symptoms of muscle weakness. In heart biopsies of both patients, dystrophin—the protein product of DMD locus—was absent in many fibers. Dilated cardiomyopathy may be the only manifestation of dystrophin gene mutation in carriers.