RT Journal Article
SR Electronic
T1 MRI pallidal hyperintensity and brain atrophy in cirrhotic patients
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 2570
OP 2570
DO 10.1212/WNL.43.12.2570
VO 43
IS 12
A1 Kulisevsky, J.
A1 Pujol, J.
A1 Junqué, C.
A1 Deus, J.
A1 Balanzó, J.
A1 Capdevila, A.
YR 1993
UL http://n.neurology.org/content/43/12/2570.abstract
AB In cirrhotic patients, even in a stable nonencephalopathic state, MRI may show cerebral atrophy and increased signal in globus pallidus on T1-weighted sequences. We investigated the relationship between cerebral atrophy and increased pallidal signal and the clinical status of 30 cirrhotic patients. We found a weak association between the two MRI findings. There were different patterns of clinical variables related to the imaging findings. Performance on motor tasks involving speed correlated with the pallidal signal and plasma ammonia levels but not with atrophy. Test results for memory and frontal-premotor function were associated with brain atrophy but not with the pallidal signal or with ammonia.