PT  - JOURNAL ARTICLE
AU  - Baronti, F.
AU  - Mouradian, M. M.
AU  - Conant, K. E.
AU  - Giuffra, M.
AU  - Brughitta, G.
AU  - Chase, T. N.
TI  - Partial dopamine agonist therapy of levodopa‐induced dyskinesias
AID  - 10.1212/WNL.42.6.1241
DP  - 1992 Jun 01
TA  - Neurology
PG  - 1241--1241
VI  - 42
IP  - 6
4099  - http://n.neurology.org/content/42/6/1241.short
4100  - http://n.neurology.org/content/42/6/1241.full
SO  - Neurology1992 Jun 01; 42
AB  - We administered the partial dopamine agonist terguride under controlled conditions to patients with Parkinson's disease (PD), both as monotherapy and in conjunction with intravenous levodopa. Terguride produced a dose-dependent decrease in levodopa-induced dyskinesias (up to 53%) in seven patients without concomitant worsening of parkinsonism, and had no significant antiparkinsonian effect when administered alone. Partial dopamine agonists may hold some promise in the adjuvant therapy of patients with advanced PD.