RT Journal Article SR Electronic T1 The Neuropsychiatric Inventory JF Neurology JO Neurology FD Lippincott Williams & Wilkins SP 2308 OP 2308 DO 10.1212/WNL.44.12.2308 VO 44 IS 12 A1 Cummings, J. L. A1 Mega, M. A1 Gray, K. A1 Rosenberg-Thompson, S. A1 Carusi, D. A. A1 Gornbein, J. YR 1994 UL http://n.neurology.org/content/44/12/2308.abstract AB We developed a new instrument, the Neuropsychiatric Inventory (NPI), to assess 10 behavioral disturbances occurring in dementia patients: delusions, hallucinations, dysphoria, anxiety, agitation/aggression, euphoria, disinhibition, irritability/lability, apathy, and aberrant motor activity. The NPI uses a screening strategy to minimize administration time, examining and scoring only those behavioral domains with positive responses to screening questions. Both the frequency and the severity of each behavior are determined. Information for the NPI is obtained from a caregiver familiar with the patient's behavior. Studies reported here demonstrate the content and concurrent validity as well as between-rater, test-retest, and internal consistency reliability; the instrument is both valid and reliable. The NPI has the advantages of evaluating a wider range of psychopathology than existing instruments, soliciting information that may distinguish among different etiologies of dementia, differentiating between severity and frequency of behavioral changes, and minimizing administration time.