RT Journal Article
SR Electronic
T1 CSF antigliadin antibodies and the Ramsay Hunt syndrome
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 1131
OP 1133
DO 10.1212/WNL.49.4.1131
VO 49
IS 4
A1 Chinnery, P. F.
A1 Reading, P. J.
A1 Milne, D.
A1 Gardner-Medwin, D.
A1 Turnbull, D. M.
YR 1997
UL http://n.neurology.org/content/49/4/1131.abstract
AB Although the association between celiac disease and progressive myoclonic ataxia is well recognized, in each of the reported cases the neurologic features began in middle adult life and usually in patients who had clinical or laboratory evidence of malabsorption. We report a case of progressive myoclonic ataxia and epilepsy (Ramsay Hunt syndrome) that began in childhood. In this patient there were no features suggestive of gluten intolerance. The presence of antigliadin antibodies in the serum and CSF suggested celiac disease was the cause of the patient's neurologic syndrome. Duodenal morphologic abnormalities reversed with treatment but no major changes were noted in the patient. Celiac disease should be considered in the differential diagnosis of myoclonic ataxia at any age, even in the absence of clinical evidence of gluten-sensitive enteropathy.