PT  - JOURNAL ARTICLE
AU  - Tarnopolsky, Mark
AU  - Martin, Joan
TI  - Creatine monohydrate increases strength in patients with neuromuscular disease
AID  - 10.1212/WNL.52.4.854
DP  - 1999 Mar 01
TA  - Neurology
PG  - 854--854
VI  - 52
IP  - 4
4099  - http://n.neurology.org/content/52/4/854.short
4100  - http://n.neurology.org/content/52/4/854.full
SO  - Neurology1999 Mar 01; 52
AB  - Article abstract Creatine monohydrate has been shown to increase strength in studies of young healthy subjects and in a few studies with patients. Creatine monohydrate (10 g daily for 5 days to 5 g daily for 5 days) was administered to patients with neuromuscular disease in a pilot study (Study 1; n = 81), followed by a single-blinded study (Study 2; n = 21). Body weight, handgrip, dorsiflexion, and knee extensor strength were measured before and after treatment. Creatine administration increased all measured indices in both studies. Short-term creatine monohydrate increased high-intensity strength significantly in patients with neuromuscular disease.