PT - JOURNAL ARTICLE AU - Greenberg, Steven M. AU - O’Donnell, Heather C. AU - Schaefer, Pamela W. AU - Kraft, Eduard TI - MRI detection of new hemorrhages: Potential marker of progression in cerebral amyloid angiopathy AID - 10.1212/WNL.53.5.1135 DP - 1999 Sep 01 TA - Neurology PG - 1135--1135 VI - 53 IP - 5 4099 - http://n.neurology.org/content/53/5/1135.short 4100 - http://n.neurology.org/content/53/5/1135.full SO - Neurology1999 Sep 01; 53 AB - Article abstract The authors used serial gradient-echo MRIs to detect new small hemorrhages in patients with previous lobar hemorrhage. Of 24 lobar hemorrhage patients (17 diagnosed with probable and 7 with possible amyloid angiopathy) who prospectively underwent repeat MRI 1.5 years after initial study, 9 (38%) demonstrated additional hemorrhages at follow-up. Interrater agreement was high. New hemorrhages were more frequent in patients with probable amyloid angiopathy (8 of 17, 47%) with more hemorrhages at baseline (p < 0.01). These results suggest a role for gradient-echo MRI in assessing disease progression in amyloid angiopathy.