PT  - JOURNAL ARTICLE
AU  - Chinnery, P.F.
AU  - Taylor, G.A.
AU  - Howell, N.
AU  - Andrews, R.M.
AU  - Morris, C.M.
AU  - Taylor, R.W.
AU  - McKeith, I.G.
AU  - Perry, R.H.
AU  - Edwardson, J.A.
AU  - Turnbull, D.M.
TI  - Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies
AID  - 10.1212/WNL.55.2.302
DP  - 2000 Jul 25
TA  - Neurology
PG  - 302--304
VI  - 55
IP  - 2
4099  - http://n.neurology.org/content/55/2/302.short
4100  - http://n.neurology.org/content/55/2/302.full
SO  - Neurology2000 Jul 25; 55
AB  - Article abstract The authors analyzed the relationship between nuclear genetic risk factors (apolipoprotein E genotype) and mitochondrial DNA (mtDNA) sequence variants in pathologically proved cases of AD (n = 185), dementia with Lewy bodies (DLB; n = 84), and control subjects (n = 179). Specific European mtDNA haplogroups and the A4336G mutation were not associated with an increased risk of AD. mtDNA haplogroup H was overrepresented in the DLB patients when compared with control subjects. Additional studies are needed to clarify the significance of the association.