PT  - JOURNAL ARTICLE
AU  - Tirschwell, D.L.
AU  - Coplin, W.M.
AU  - Becker, K.J.
AU  - Vogelzang, P.
AU  - Eskridge, J.
AU  - Haynor, D.
AU  - Cohen, W.
AU  - Newell, D.
AU  - Winn, H.R.
AU  - Longstreth, W.T.
TI  - Intra-arterial urokinase for acute ischemic stroke
AID  - 10.1212/WNL.57.6.1100
DP  - 2001 Sep 25
TA  - Neurology
PG  - 1100--1103
VI  - 57
IP  - 6
4099  - http://n.neurology.org/content/57/6/1100.short
4100  - http://n.neurology.org/content/57/6/1100.full
SO  - Neurology2001 Sep 25; 57
AB  - The authors abstracted the records of 43 patients treated with intra-arterial urokinase for acute ischemic stroke to identify predictors of serious complications. Sixteen (37%) had such a complication. Higher urokinase dose (>1.5 × 106 U), higher mean arterial blood pressure before treatment (>130 mm Hg), basilar occlusive strokes, and severe strokes were most predictive of these complications. Although urokinase is no longer manufactured, these findings identify patients at risk for complications from other intra-arterial thrombolytics.