RT Journal Article SR Electronic T1 Linkage analysis of Alzheimer disease with psychosis JF Neurology JO Neurology FD Lippincott Williams & Wilkins SP 118 OP 120 VO 59 IS 1 A1 Bacanu, S. A. A1 Devlin, B. A1 Chowdari, K. V. A1 DeKosky, S. T. A1 Nimgaonkar, V. L. A1 Sweet, R. A. YR 2002 UL http://n.neurology.org/content/59/1/118.abstract AB Although a portion of risk for late-onset AD (LOAD) is attributable to APOE, the search for other loci is ongoing. The authors hypothesize that psychotic symptoms with LOAD (LOAD+P) identify a potentially more etiologically homogeneous form of AD. Linkage analysis of families with LOAD+P identified one significant and several suggestive novel linkage signals, which bolsters the conjecture of greater etiologic homogeneity.