PT - JOURNAL ARTICLE AU - Rocca, M. A. AU - Agosta, F. AU - Mezzapesa, D. M. AU - Martinelli, V. AU - Salvi, F. AU - Ghezzi, A. AU - Bergamaschi, R. AU - Comi, G. AU - Filippi, M. TI - Magnetization transfer and diffusion tensor MRI show gray matter damage in neuromyelitis optica AID - 10.1212/01.WNL.0000106946.08741.41 DP - 2004 Feb 10 TA - Neurology PG - 476--478 VI - 62 IP - 3 4099 - http://n.neurology.org/content/62/3/476.short 4100 - http://n.neurology.org/content/62/3/476.full SO - Neurology2004 Feb 10; 62 AB - Using magnetization transfer (MT) and diffusion tensor (DT) MRI, the authors assessed the extent of tissue damage of the brain normal-appearing white and gray matter (NAGM) in patients with neuromyelitis optica (NMO). Compared to healthy controls, patients with NMO showed reduced MT ratio and increased mean diffusivity of the NAGM. This challenges the classic notion of a sparing of the brain tissue in the course of NMO.