PT  - JOURNAL ARTICLE
AU  - Ohayon, Maurice
TI  - Refining the frequency and duration of RL Symptoms: Impact on the prevalence of Restless Leg Syndrome (P3.062)
DP  - 2017 Apr 18
TA  - Neurology
PG  - P3.062
VI  - 88
IP  - 16 Supplement
4099  - http://n.neurology.org/content/88/16_Supplement/P3.062.short
4100  - http://n.neurology.org/content/88/16_Supplement/P3.062.full
SO  - Neurology2017 Apr 18; 88
AB  - Objective: Finding the most appropriate thresholds for frequency and duration of RLS symptoms in order to assess more accurately the prevalence of RLS in the general population in addition to the comorbid medical, sleep and mental disorders.Background: Using the IRLSSG criteria, prevalence of RL ranged from 3.9 to 14.3%. The minimal diagnosis criteria now include the mimics exclusion criteria and the merging of pediatric and adult criteria. By adding an exclusion criterion for mimics, the specificity of the disorder was increased. However, duration and frequency impact on the prevalence is still unknown.Design/Methods: A representative sample of the US population interviewed by phone with the SleepEVAL system (19,136 individuals 18 years and older; participation rate 83.2% according to CASRO standards).Results: Prevalence of the four criteria occurring at least one day per week ranged between 5.7 and 12.3%. When frequency is at 3 or more days by week, prevalence drops to 1.8–4.5%, with greater distress and impairment.Conclusions: Stricter criteria definition avoids the inflation of the prevalence RLS diagnosis with, as a consequence, more appropriate therapeutic indications.Disclosure: Dr. Ohayon has received personal compensation for activities with Sanofi-Aventis Pharmaceuticals, Inc. as a speaker. Dr. Ohayon has received research support from Jazz Pharmaceuticals and Takeda Pharmaceuticals.