RT Journal Article
SR Electronic
T1 Dehydration confounds the assessment of brain atrophy
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 548
OP 550
DO 10.1212/01.WNL.0000150542.16969.CC
VO 64
IS 3
A1 T. Duning
A1 S. Kloska
A1 O. Steinsträter
A1 H. Kugel
A1 W. Heindel
A1 S. Knecht
YR 2005
UL http://n.neurology.org/content/64/3/548.abstract
AB Computerized brain volumetry has potential value for diagnosis and the follow-up evaluation of degenerative disorders. A potential pitfall of this method is the extent of physiologic variations in brain volume. The authors show that dehydration and rehydration can significantly change brain volume: lack of fluid intake for 16 hours decreased brain volume by 0.55% (SD, ±0.69), and after rehydration total cerebral volume increased by 0.72% (SD, ±0.21).