PT  - JOURNAL ARTICLE
AU  - Whitwell, Jennifer L.
AU  - Jack, Clifford R.
AU  - Senjem, Matthew L.
AU  - Josephs, Keith A.
TI  - Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration
AID  - 10.1212/01.wnl.0000191395.69438.12
DP  - 2006 Jan 10
TA  - Neurology
PG  - 102--104
VI  - 66
IP  - 1
4099  - http://n.neurology.org/content/66/1/102.short
4100  - http://n.neurology.org/content/66/1/102.full
SO  - Neurology2006 Jan 10; 66
AB  - The authors used voxel-based morphometry to compare the patterns of brain atrophy in two variants of pathologically confirmed frontotemporal lobar degeneration (FTLD): FTLD with motor neuron disease (FTLD-MND) and FTLD with ubiquitin-only-immunoreactive neuronal changes (FTLD-U). Patterns of atrophy were distinct and different from each other. A localized pattern of frontal lobe atrophy was found in FTLD-MND with a more widespread pattern of atrophy affecting the frontal and temporal lobes in FTLD-U.