PT  - JOURNAL ARTICLE
AU  - Aydin, K.
AU  - Tatli, B.
AU  - Ozkan, M.
AU  - Ciftci, K.
AU  - Unal, Z.
AU  - Sani, S.
AU  - Ozmen, M.
AU  - Caliskan, M.
AU  - Aydinli, N.
AU  - Guven, S.
TI  - Quantification of neurometabolites in subacute sclerosing panencephalitis by <sup>1</sup>H-MRS
AID  - 10.1212/01.wnl.0000233836.16266.f5
DP  - 2006 Sep 12
TA  - Neurology
PG  - 911--913
VI  - 67
IP  - 5
4099  - http://n.neurology.org/content/67/5/911.short
4100  - http://n.neurology.org/content/67/5/911.full
SO  - Neurology2006 Sep 12; 67
AB  - The authors studied 20 patients with subacute sclerosing panencephalitis (SSPE) to investigate the correlations between MRI, magnetic resonance spectroscopy (MRS), and clinical status. MRI findings did not correlate with clinical status. By contrast, all patients had reductions in N-acetyl aspartate (NAA) and increase in myoinositol (mI) (p < 0.01), and NAA and mI concentrations correlated with clinical severity (p < 0.05). During follow-up, NAA continued to decline. 1H-MRS may be a useful measure of disease severity and progression in SSPE.