RT Journal Article
SR Electronic
T1 Quantification of neurometabolites in subacute sclerosing panencephalitis by <sup>1</sup>H-MRS
JF Neurology
JO Neurology
FD Lippincott Williams &amp; Wilkins
SP 911
OP 913
DO 10.1212/01.wnl.0000233836.16266.f5
VO 67
IS 5
A1 Aydin, K.
A1 Tatli, B.
A1 Ozkan, M.
A1 Ciftci, K.
A1 Unal, Z.
A1 Sani, S.
A1 Ozmen, M.
A1 Caliskan, M.
A1 Aydinli, N.
A1 Guven, S.
YR 2006
UL http://n.neurology.org/content/67/5/911.abstract
AB The authors studied 20 patients with subacute sclerosing panencephalitis (SSPE) to investigate the correlations between MRI, magnetic resonance spectroscopy (MRS), and clinical status. MRI findings did not correlate with clinical status. By contrast, all patients had reductions in N-acetyl aspartate (NAA) and increase in myoinositol (mI) (p &lt; 0.01), and NAA and mI concentrations correlated with clinical severity (p &lt; 0.05). During follow-up, NAA continued to decline. 1H-MRS may be a useful measure of disease severity and progression in SSPE.