PT  - JOURNAL ARTICLE
AU  - Winterkorn, Elisabeth B.
AU  - Pulsifer, Margaret B.
AU  - Thiele, Elizabeth A.
TI  - Cognitive prognosis of patients with tuberous sclerosis complex
AID  - 10.1212/01.wnl.0000250330.44291.54
DP  - 2007 Jan 02
TA  - Neurology
PG  - 62--64
VI  - 68
IP  - 1
4099  - http://n.neurology.org/content/68/1/62.short
4100  - http://n.neurology.org/content/68/1/62.full
SO  - Neurology2007 Jan 02; 68
AB  - To assess cognitive outcome in patients with tuberous sclerosis complex (TSC) and identify predictive risk factors, we reviewed records of 107 patients who underwent comprehensive neuropsychiatric evaluation. Fifty-seven percent of patients with TSC had normal-range IQ/developmental quotient (DQ). Cognitive outcome was strongly associated with refractory seizures and TSC2 mutation. In TSC, IQ/DQ is bimodally distributed, and more than half of individuals are in the normal range.