RT Journal Article
SR Electronic
T1 Cognitive prognosis of patients with tuberous sclerosis complex
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 62
OP 64
DO 10.1212/01.wnl.0000250330.44291.54
VO 68
IS 1
A1 Winterkorn, Elisabeth B.
A1 Pulsifer, Margaret B.
A1 Thiele, Elizabeth A.
YR 2007
UL http://n.neurology.org/content/68/1/62.abstract
AB To assess cognitive outcome in patients with tuberous sclerosis complex (TSC) and identify predictive risk factors, we reviewed records of 107 patients who underwent comprehensive neuropsychiatric evaluation. Fifty-seven percent of patients with TSC had normal-range IQ/developmental quotient (DQ). Cognitive outcome was strongly associated with refractory seizures and TSC2 mutation. In TSC, IQ/DQ is bimodally distributed, and more than half of individuals are in the normal range.