PT  - JOURNAL ARTICLE
AU  - Cheng-Ching, Esteban
AU  - Samaniego, Edgar A.
AU  - Naravetla, Bharath Reddy
AU  - Zaidat, Osama O.
AU  - Hussain, Muhammad Shazam
TI  - Update on pharmacology of antiplatelets, anticoagulants, and thrombolytics
AID  - 10.1212/WNL.0b013e3182695871
DP  - 2012 Sep 25
TA  - Neurology
PG  - S68--S76
VI  - 79
IP  - 13 Supplement 1
4099  - http://n.neurology.org/content/79/13_Supplement_1/S68.short
4100  - http://n.neurology.org/content/79/13_Supplement_1/S68.full
SO  - Neurology2012 Sep 25; 79
AB  - Understanding of the pharmacology of thrombolytics, anticoagulants, and antiplatelets is critical to performing safe and effective endovascular therapy for acute ischemic therapy. This is a basic review of the clinical pharmacologic data on the anticoagulants, antiplatelets, and fibrinolytic agents most commonly used in the treatment of stroke and in the neurointerventional suite. CYP=cytochrome P450; FDA=US Food and Drug Administration; HIT=heparin-induced thrombocytopenia; LMWH=low-molecular-weight heparin; Pro-UK=prourokinase; rtPA=recombinant tissue plasminogen activator; tPA=tissue plasminogen activator; UFH=unfractionated heparin; VTE=venous thromboembolism