PT - JOURNAL ARTICLE AU - Cragg, Jacquelyn J. AU - Noonan, Vanessa K. AU - Krassioukov, Andrei AU - Borisoff, Jaimie TI - Cardiovascular disease and spinal cord injury AID - 10.1212/WNL.0b013e3182a1aa68 DP - 2013 Aug 20 TA - Neurology PG - 723--728 VI - 81 IP - 8 4099 - http://n.neurology.org/content/81/8/723.short 4100 - http://n.neurology.org/content/81/8/723.full SO - Neurology2013 Aug 20; 81 AB - Objective: To evaluate the association between cardiovascular disease (CVD) and spinal cord injury (SCI) in a large representative sample.Methods: Data were compiled from more than 60,000 individuals from the 2010 cycle of the cross-sectional Canadian Community Health Survey (CCHS). Multivariable logistic regression analysis was conducted to examine this relationship, adjusting for confounders and using probability weighting to account for the CCHS sampling method.Results: After adjusting for age and sex, SCI was associated with a significant increased odds of heart disease (adjusted odds ratio [OR] = 2.72, 95% confidence interval [CI] 1.94–3.82) and stroke (adjusted OR = 3.72, 95% CI 2.22–6.23).Conclusions: These remarkably heightened odds highlight the exigent need for targeted interventions and prevention strategies addressing modifiable risk factors for CVD in individuals with SCI.CCHS=Canadian Community Health Survey; CI=confidence interval; CVD=cardiovascular disease; MI=myocardial infarction; OR=odds ratio; SCI=spinal cord injury