PT  - JOURNAL ARTICLE
AU  - Cragg, Jacquelyn J.
AU  - Noonan, Vanessa K.
AU  - Krassioukov, Andrei
AU  - Borisoff, Jaimie
TI  - Cardiovascular disease and spinal cord injury
AID  - 10.1212/WNL.0b013e3182a1aa68
DP  - 2013 Aug 20
TA  - Neurology
PG  - 723--728
VI  - 81
IP  - 8
4099  - http://n.neurology.org/content/81/8/723.short
4100  - http://n.neurology.org/content/81/8/723.full
SO  - Neurology2013 Aug 20; 81
AB  - Objective: To evaluate the association between cardiovascular disease (CVD) and spinal cord injury (SCI) in a large representative sample.Methods: Data were compiled from more than 60,000 individuals from the 2010 cycle of the cross-sectional Canadian Community Health Survey (CCHS). Multivariable logistic regression analysis was conducted to examine this relationship, adjusting for confounders and using probability weighting to account for the CCHS sampling method.Results: After adjusting for age and sex, SCI was associated with a significant increased odds of heart disease (adjusted odds ratio [OR] = 2.72, 95% confidence interval [CI] 1.94–3.82) and stroke (adjusted OR = 3.72, 95% CI 2.22–6.23).Conclusions: These remarkably heightened odds highlight the exigent need for targeted interventions and prevention strategies addressing modifiable risk factors for CVD in individuals with SCI.CCHS=Canadian Community Health Survey; CI=confidence interval; CVD=cardiovascular disease; MI=myocardial infarction; OR=odds ratio; SCI=spinal cord injury