RT Journal Article
SR Electronic
T1 Efficacy of EPA Enriched Phosphatidylserine-Omega-3 (Vayarin) on Children with ADHD (P7.336)
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP P7.336
VO 82
IS 10 Supplement
A1 Nguyen, Stephanie
A1 Nguyen, Cindy
A1 Chudnow, Robert
A1 Miller, Van
A1 Riela, Anthony
A1 So, Gerald
A1 Mireles, Patricia
A1 Shah, Lina
YR 2014
UL http://n.neurology.org/content/82/10_Supplement/P7.336.abstract
AB OBJECTIVE: To determine if Vayarin is a plausible treatment for long-term ADHD management. BACKGROUND: The FDA approved medical food, Vayarin, is a phosphatidylserine-omega-3 that is EPA enriched and is intended to reduce ADHD symptoms. ADHD patient families are motivated to try non-stimulant medication therapy that might benefit the condition. Vayarin retails for $60 per month and lacks insurance coverage. Most families front the cost of treatment. DESIGN/METHODS: Texas Child Neurology's electronic health records (EHR) retrospectively identified 722 unique patients diagnosed with ADHD who had been prescribed Vayarin therapy for a potential of at least 3 months. Successful therapy was defined as continued treatment beyond 3 months and patient data was stratified into result groups based upon this premise. Information from chart review and telephone interview of parents garnered reasons for results of treatment. Quantification of therapy effect was based upon gathered information. RESULTS: Of the 722 unique patients, 300 patients met criteria for 3 months therapy. Co-treatment with stimulant medication occurred in 43.3%. Two-hundred forty-five (81.7%) continued Vayarin therapy beyond 3 months. Of these, 31.3% were definite beneficiaries of Vayarin. Another 29.7% reported some benefit. The remaining 20.7% reported no benefit but continued Vayarin regardless. A significant portion of the patient sample failed to use Vayarin for the required 3 months. Two-hundred and seven of the sample (28.7%) were lost to follow-up. Another 12.9% never filled the prescription. One-hundred twenty-two (16.9%) of the sample have incomplete information. Many of these are known to have quit Vayarin therapy prior to 3 months treatment (40.2%). CONCLUSIONS: Vayarin is a novel therapy for ADHD that appears to be effective. Approximately 60% of the users who completed 3 months therapy reported benefit of treatment. A slow response time of 3 months is an impediment to successful management as only 41.6% of subjects prescribed Vayarin remained compliant for the duration. Cost and patient objection to Vayarin taste are prominent reasons for therapy failure. Disclosure: Dr. Nguyen has nothing to disclose. Dr. Nguyen has nothing to disclose. Dr. Chudnow has received personal compensation for activities with Vaya Pharma as a speaker. Dr. Miller has nothing to disclose. Dr. Riela has received personal compensation for activities with Vaya Pharma as a speaker. Dr. So has nothing to disclose. Dr. Mireles has nothing to disclose. Dr. Shah has nothing to disclose.Thursday, May 1 2014, 3:00 pm-6:30 pm