Table 3.

COMPASS and validity subscores in the three subject groups

Domains	Maximal possible score^*	Normal control (NML), n = 41			Peripheral neuropathy (PN), n = 33			Neurogenic autonomic failure (NAF), n = 39			p Value^‡
Domains	Maximal possible score^*	Mean	% >0^†	Range	Mean	% >0^†	Range	Mean	% >0^†	Range	NAF vs NML	NAF vs PN
* The lowest possible score is 0 for all domains.
† % >0: percent of people with a score greater than 0.
‡ p values associated with Wilcoxon rank sum tests.
COMPASS = Composite Autonomic Symptom Scale; NS = not statistically significant, p > 0.05.
Orthostatic intolerance	40	3.6	34.2	0–17.5	8.4	51.5	0–32.5	21.6	89.7	0–37.5	<0.001	<0.001
Secretomotor	20	0.9	31.7	0–6.2	3.7	75.8	0–12.3	6.5	94.9	0–16.9	<0.001	0.002
Male sexual dysfunction	30	0.6	21.7	0–8.6	5.8	75.0	0–12.9	9.5	71.4	0–19.3	<0.001	NS
Urinary	20	0.8	31.7	0–4	1.3	45.5	0–8	2.9	69.2	0–14	<0.001	0.014
Gastroparesis	10	0.5	22.0	0–5.7	0.7	36.4	0–4.3	2.4	59.0	0–10	<0.001	0.006
Diarrhea	20	1.5	29.3	0–8	2.8	33.3	0–16	4.2	46.2	0–16	0.022	NS
Constipation	10	0.6	34.2	0–7.1	1.1	42.4	0–7.1	2.5	66.7	0–10	<0.001	0.018
Pupillomotor	5	0.4	36.6	0–1.8	0.7	60.6	0–4.1	1.6	82.1	0–4.5	<0.001	0.006
Vasomotor	10	0.4	7.3	0–6.3	2.3	39.4	0–7.5	2.2	38.5	0–8.1	<0.001	NS
Reflex syncope	20	0	0	0–0	0.2	6.1	0–4.0	0.9	23.1	0–4.0	0.001	0.048
Sleep	15	0.8	34.2	0–6	1.8	57.6	0–8.3	2.4	56.4	0–12	0.009	NS
Validity scales
Understatement index	10	1.3	46.3	0–5	2.0	57.6	0–8.3	2.6	64.1	0–10	0.05	NS
Psychosomatic index	10	0.0	2.4	0–1.8	0.1	9.1	0–2.7	0.6	17.9	0–6.3	0.02	NS