Demographic and clinical characteristics of the patients with the different MS clinical phenotypes studied
| CIS | RRMS | SPMS | BMS | PPMS | |
|---|---|---|---|---|---|
| CIS = clinically isolated syndrome; RRMS = relapsing-remitting MS; SPMS = secondary progressive MS; BMS = benign MS; PPMS = primary progressive MS; EDSS = Expanded Disability Status Scale. | |||||
| Number of patients | 21 | 42 | 30 | 11 | 10 |
| Male/female ratio | 0.9 | 0.5 | 0.4 | 0.6 | 4.0 |
| Mean age (SD), y | 27.7 (5.3) | 31.7 (7.2) | 37.9 (8.5) | 41.5 (5.4) | 46.6 (9.1) |
| Median duration of disease (range), y | — | 5 (1–20) | 8 (3–24) | 15 (15–20) | 8 (3–30) |
| Median EDSS (range) | 1.0 (0–2.0) | 2.5 (1.0–6.5) | 5.5 (3.5–7.0) | 1.0 (0–1.5) | 4.0 (2.0–8.0) |