Table 2.

Lesion loads on T2- and T1-weighted scans in the different clinical phenotypes studied

CISRRMSSPMSBMSPPMS
See the text for statistical analysis.
CIS = clinically isolated syndrome; RRMS = relapsing-remitting MS; SPMS = secondary progressive MS; BMS = benign MS; PPMS = primary progressive MS.
Number of patients2142301110
T2 lesion load (mL)
Median5.314.123.98.34.3
Range1.8–25.40.7–68.82.4–100.62.6–30.80.9–18.6
Mean ± SD6.7 ± 5.319.4 ± 16.832.8 ± 23.911.8 ± 9.26.1 ± 5.7
Hypointense T1 lesion load (mL)
Median0.10.94.90.50.1
Range0–1.00.0–35.60.0–47.20.0–3.20.0–0.7
Mean ± SD0.2 ± 0.23.0 ± 6.79.1 ± 10.80.8 ± 0.90.2 ± 0.2
T1/T2 ratio
Median0.020.070.190.050.05
Range0–0.090–0.510–0.700–0.130–0.06
Mean ± SD0.03 ± 0.030.12 ± 0.140.24 ± 0.170.07 ± 0.040.04 ± 0.02