Magnetization transfer metrics in controls and in the different MS phenotypes studied
| Controls | CIS | RRMS | SPMS | BMS | PPMS | |
|---|---|---|---|---|---|---|
| See the text for statistical analysis. | ||||||
| CIS = clinically isolated syndrome; RRMS = relapsing-remitting MS; SPMS = secondary progressive MS; BMS = benign MS; PPMS = primary progressive MS; MTR = magnetization transfer ratio. | ||||||
| Number of patients | 20 | 21 | 42 | 30 | 11 | 10 |
| Average brain MTR (%) | 45.8 ± 0.9 | 45.6 ± 1.3 | 43.1 ± 3.0 | 42.0 ± 4.2 | 44.9 ± 0.9 | 44.5 ± 1.8 |
| MTR25 (%) | 35.9 ± 1.2 | 35.6 ± 1.8 | 31.9 ± 4.0 | 30.1 ± 5.8 | 34.9 ± 1.4 | 32.8 ± 3.1 |
| MTR50 (%) | 41.8 ± 1.1 | 41.8 ± 1.3 | 39.4 ± 3.5 | 38.0 ± 4.8 | 41.4 ± 1.0 | 41.0 ± 1.8 |
| MTR75 (%) | 45.9 ± 0.9 | 45.8 ± 1.2 | 43.6 ± 3.2 | 42.7 ± 4.3 | 45.4 ± 0.9 | 46.1 ± 1.2 |
| Peak height | 63.2 ± 5.4 | 64.5 ± 5.4 | 58.6 ± 7.0 | 58.2 ± 8.6 | 63.8 ± 5.9 | 55.5 ± 9.4 |
| Peak position (%) | 43.9 ± 1.1 | 43.9 ± 1.4 | 42.1 ± 3.3 | 41.3 ± 4.1 | 43.7 ± 0.9 | 44.2 ± 1.5 |
| Average lesion MTR (%) | — | 40.3 ± 1.9 | 38.0 ± 3.7 | 36.8 ± 4.5 | 39.8 ± 1.7 | 40.6 ± 2.9 |