Number and index of PLMS and PLMW for 10 RLS patients in the four conditions (mean ± standard deviation)
| Baseline | Withdrawal | Placebo | Pramipexole | Crossover analysis p* | |
|---|---|---|---|---|---|
| * Mann-Whitney U tests. | |||||
| † Number of PLMS with arousal. | |||||
| PLMS = periodic leg movements during sleep; PLMW = periodic leg movements during wakefulness; RLS = restless legs syndrome. | |||||
| PLMS number | 465.7 ± 273.4 | 448.1 ± 253.5 | 452.5 ± 251.4 | 10.6 ± 18.7 | 0.01 |
| PLMS index | 77.1 ± 47.5 | 65.5 ± 34.1 | 68.0 ± 39.7 | 1.7 ± 3.1 | 0.01 |
| PLMS arousal† | 11.0 ± 6.6 | 8.6 ± 3.2 | 8.8 ± 7.2 | 0.8 ± 1.3 | 0.01 |
| PLMW number | 137.2 ± 154.8 | 82.4 ± 85.2 | 103.3 ± 116.2 | 17.2 ± 21.8 | 0.01 |
| PLMW index | 66.4 ± 54.0 | 65.1 ± 45.7 | 64.3 ± 50.3 | 13.5 ± 12.2 | 0.01 |