Table 2.

Results

Vigabatrin, n = 21ACTH, n = 21p Value
Values are n (%).
* Statistically significant differences, using chi-square or t-test as required.
Spasm response
Total16 (76)18 (86)0.43
Complete14 (67)14 (67)1.00
Partial2 (10)4 (19)
EEG response
Total15 (75)15 (71)0.80
Complete8 (40)12 (57)0.27
Partial7 (35)3 (14)
Relapsing spasm
3 mo0/16 (0)*4/18 (22)*0.05
6 mo0/16 (0)*4/16 (25)*0.03
12 mo1/16 (6)4/15 (27)0.12
Seizure relapse
3 mo1/16 (6)2/18 (11)0.62
6 mo4/16 (25)5/16 (31)0.69
12 mo5/16 (31)6/15 (40)0.61
Development (latest)
Normal5 (24)7 (33)0.50
Moderate delay8 (38)8 (38)1.00
Severe delay8 (38)6 (39)0.51
Development (outcome)
Improved7 (33)6 (29)0.74
Stable10 (48)10 (48)1.00
Worse4 (19)5 (24)0.71