Table 2.

Clinical features for qualitative variables of all and unrelated patients in 87 sibpairs concordant for MS

All patientsUnrelated patients
n (%)95% CIn (%)95% CI
CI = confidence interval; HLA (human leukocyte antigen) DRX/X = no HLA DR15 haplotype; HLA DR15/X = heterozygous for HLA DR15; HLA DR15/15 = homozygous for HLA DR15; RR = relapsing-remitting; SP = secondary progressive; PP = primary progressive.
Sex
Male58 (32.8)26–4028 (32.2)22–43
Female119 (67.2)59–7459 (67.8)56–77
HLA
DRX/X105 (58.8)51–6547 (55.9)44–66
DR15/X65 (36.9)30–4436 (42.9)32–54
DR15/157 (4.3)2.0–8.61 (1.2)0.0–6.5
Disease course
RR109 (61.3)53–6852 (62.7)51–73
SP59 (33.3)26–4025 (30.1)20–41
PP9 (5.4)2.8–10.06 (7.2)2.70–15.1