Table 1.

Frequency and degree of white matter hyperintensity (WMH) change after 3 years

VariableRater 1, n (%)Rater 2, n (%)Rater 3, n (%)Combined, n (%)
WMH grade
−18 (2.9)1 (0.4)00
0249 (91.2)248 (90.8)254 (93.0)253 (92.7)
+116 (5.9)24 (8.8)16 (5.9)20 (7.3)
WMH number
−1 to 414 (5.1)2 (0.7)00
0199 (72.9)214 (78.4)222 (81.3)224 (82.1)
+1 to 447 (17.2)39 (14.3)31 (11.4)32 (11.7)
+5 to 911 (4.0)9 (3.3)4 (1.5)7 (2.6)
>92 (0.7)9 (3.3)4 (1.5)7 (2.6)
WMH progression
Total60 (22.0)57 (20.9)48 (17.6)49 (17.9)
Minor41 (15.0)33 (12.1)27 (9.9)27 (9.9)
Marked19 (7.0)24 (8.8)21 (7.7)22 (8.1)