Table 1.

Motor and ADL scores before surgery and at regular follow-up visits for patients with stimulation

VariableBaseline1 Month3 Months6 Months12 MonthsLast visit
* Percent variation in the UPDRS motor score in best “on” compared with worst “off.”
† Compared with baseline.
‡ In contrast to the UPDRS, an increase in the score indicates an improvement.
UPDRS = Unified Parkinson’s Disease Rating Scale; ADL = activities of daily living; LEDD = levodopa-equivalent daily dose.
UPDRS ADL score
Off drug, mean score ± SD36.1 ± 5.319.4 ± 9.118.6 ± 8.918.2 ± 8.518.8 ± 8.617.3 ± 7.9
On drug, mean score ± SD15.3 ± 8.713.4 ± 7.614.3 ± 10.613.5 ± 915.8 ± 8.614.3 ± 7.7
Percent change off drug−46.2−48.6−49.7−48−52.2
Percent change on drug−12.1−6.5−11.73.4−6.5
UPDRS motor score
Off drug, mean score ± SD67.6 ± 9.945.3 ± 15.644.6 ± 1343.5 ± 11.539.8 ± 10.939.3 ± 12.0
On drug, mean score ± SD29.3 ± 9.432.9 ± 1534.7 ± 14.131.7 ± 12.232.4 ± 11.530.7 ± 13.1
Maximal on/off fluctuation,* %56.727.422.227.118.621.9
Percent change off drug−33.0−34.0−35.6−41.1−41.9
Percent change on drug12.218.58.110.64.9
Schwab & England Scale
Off drug, mean score ± SD21.4 ± 12.154.3 ± 2367.1 ± 18.068.3 ± 20.462.0 ± 21.767.1 ± 19.8
On drug, mean score ± SD70.0 ± 14.177.1 ± 18.078.6 ± 14.680.0 ± 15.578.0 ± 16.480.0 ± 14.1
Percent change off drug153.3213.3218.9189.3213.3
Percent change on drug10.212.214.311.414.3
LEDD, mean ± SD1507.3 ± 821.5600.4 ± 137.4558.7 ± 124.9526.7 ± 106.8535.8 ± 87.9521.3 ± 90.4
Percent change LEDD−60.2−62.9−65.1−64.5−65.4
Energy delivered per patient (W × 10−6 ± SD)2.0 ± 1.01.9 ± 0.92.3 ± 0.62.9 ± 1.52.7 ± 1.4
Patients, n777657